Build a custom plague through mutation trees and strategic upgrades as you watch infection spread across the globe in this incremental outbreak simulator. Balance pathogen traits to maximize transmission while unlocking new disease types and permanent progression boosts that persist through resets. Ideal for players who enjoy dark humor, deep upgrade systems, and the satisfaction of watching exponential growth unfold with minimal input.
About this game
Patient Zero: Plague Idle is an idle / incremental outbreak builder where you create the perfect pathogen through mutation trees, global infection, long-term upgrades, and new pathogen unlocks. Turn the world into your lab.
Players, last 68 days
Peak 0 · Low 0
Daily peak concurrent players, sampled once a night from Steam.
The outbreak begins soon.Patient Zero: Plague Idle is joining Steam Next Fest, October 19–26!For the first time, you'll be able to dive into the free demo and start engineering your own global outbreak.Experiment with mutations, spread your pathogen across the world, automate your infection, and build increasingly powerful strains as humanity races to stop you.In the demo, you'll get a first taste of the core Patient Zero loop:Harvest Biomass to fuel your expansionAutomate your infection and increase your IPSMutate through powerful evolution pathsSpread across the globe and overcome regional defensesGrow stronger through long-term progressionSteam Next Fest begins October 19 and runs through October 26.Play the demo, let us know what you think, and if you like what you see, add Patient Zero: Plague Idle to your Wishlist.Can you engineer the ultimate extinction event?The evolution begins at Steam Next Fest.
Posts come from Steam's official announcements feed.
